Abstract Library

#2904 Prognosis and Management of Advanced Digestive Well-Differentiated Grade 3 Neuroendocrine Tumors (G3 NETs): A NET-CONNECT Study Performed in Four Expert Centers

Introduction: G3 NETs are rare tumors with poorly defined prognosis and management.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: de Mestier L, Lamarca A, Hernando-Cubero J, Alonso Gordoa T, Cros J,

Keywords: grade 3, prognosis, treatment, alkylating agents,

#2828 G3 Neuroendocrine Tumours and Carcinomas: Clinicopathological Features for Distinct Entities

Introduction: The 2019 WHO subclassified the grade 3 (G3) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) into neuroendocrine carcinoma (NEC) or tumors (G3 NET). Yet, few data exist on clinical and treatment profiles for G3 NET.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Taboada R

Authors: Taboada R, Claro L, Campos F, Felismino T, de Jesus V,

Keywords: neuroendocrine, high grade, clinicopathological, carcinoma, G3,

#2293 Genomic and Transcriptomic Characterization of Aggressive Well Differentiated Pancreatic Neuroendocrine Tumors (WD PanNET)

Introduction: While the genomic and transcriptomic landscape of low proliferating PanNET have been well studied, pathways driving aggressive WD PanNET are still unclear.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Cros J, Soukeur M, Raffenne J, Bernard V, Scoazec J,

Keywords: Exome sequencing, Pancreatic NET, G3 NET,

#2279 Expression of FOXM1 in G3 Neuroendocrine Tumors (NET G3) and G3 Neuroendocrine Carcinomas (NEC G3) of the Pancreas and the Intestine

Introduction: G3 gastroenteropancreatic neuroendocrine tumors (G3 NET) and carcinomas (G3 NEC) differ considerably concerning their biological behavior and patients outcome. Whereas the WHO2017 classification for pancreatic NETs proposes a distinction of both groups using the Ki-67 proliferation marker (Klöppel et al. Reviews and Reports 2017), a useful marker for the subclassification of G3 intestinal NETs have not been recommended until now.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Briest F

Authors: Briest F, Konukiewitz B, Anlauf M, Klöppel G, Grabowski P,

Keywords: gastroenteropancreatic neuroendocrine tumors, GEP-NET, NET G3, NEC G3, Tumor marker, FOXM1, Ki-67, differentiation,

#1693 A Better Ki-67 Index Cutoff to Redefine Low Grade NET and High Grade NEC in Grade 3 Gastroenteropancreatic Neuroendocrine Neoplasms

Introduction: Heterogeneity of Grade 3 (G3) gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) was reported and well-differentiated G3 NET (neuroendocrine tumor) was classified by previous studies.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Shi H

Authors: Shi H, Chen L, Zhang Q, Han C, Ding Z,

Keywords: gastroenteropancreatic neuroendocrine neoplasms, Ki67 index, prognostic factors,